Metilirovanie DNK u rasteniy: mehanizmyi i biologicheskaya rol. (Timiryaz. cht.)

  • Series: Timiryazev readings
  • Publisher: M.: Nauka
  • ISBN: 978-5-02-036708-1
  • Year: 2009
  • Pages: 77
  • Chief Editor: Vanyushin B. F.

PRICE: 88 rub.

Description of the book:

Nastoyaschee chtenie odnogo iz pionerov i izvestnyih mirovyih liderov v izuchenii metilirovaniya DNK u raznyih organizmov obstoyatelno izlagaet segodnyashnee sostoyanie obshebiologicheskoy problemyi, kasayuscheysya haraktera, molekulyarnyih mehanizmov i biologicheskoy roli etoy prirodnoy modifikatsii genomov u eukariot, i v osobennosti u vyisshih rasteniy. Enzimaticheskoe metilirovanie DNK s obrazovaniem ostatkov 5-me-tiltsitozina v spetsifichnyih nukleotidnyih posledovatelnostyah genoma kontroliruet rost i razvitie rasteniy i jivotnyih i uchastvuet v pereprogrammirovanii yadra na raznyih etapah ontogeneza, v tom chisle i pod vliyaniem razlichnyih biologicheskih i abioticheskih agentov i faktorov sredyi. Ono vido-, tkane- i organoidospetsifichno, izmenyaetsya s vozrastom i reguliruetsya gormonalno. Metilirovanie DNK kontroliruet vse geneticheskie protsessyi v kletke (replikatsiya, transkriptsiya, reparatsiya DNK, rekombinatsiya, transpozitsiya genov), ono yavlyaetsya mehanizmom kletochnoy i polovoy differentsirovki i genomnogo imprintinga.
Dlya biologov, biotehnologov, medikov, himikov.